Search on: GENE PRODUCTS, RAS 
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Descriptor English:   ras Proteins 
Descriptor Spanish:   Proteínas ras 
Descriptor Portuguese:   Proteínas ras 
Synonyms English:   ras GTPases
GTPases, ras
ras Gene Products
Gene Products, ras  
Tree Number:   D08.811.277.040.330.300.400.500
D12.644.360.525.500
D12.776.157.325.515.500
D12.776.476.525.500
Definition English:   Small, monomeric GTP-binding proteins encoded by ras genes (GENES, RAS). The protooncogene-derived protein, PROTO-ONCOGENE PROTEIN P21(RAS), plays a role in normal cellular growth, differentiation and development. The oncogene-derived protein (ONCOGENE PROTEIN P21(RAS)) can play a role in aberrant cellular regulation during neoplastic cell transformation (CELL TRANSFORMATION, NEOPLASTIC). This enzyme was formerly listed as EC 3.6.1.47. 
Indexing Annotation English:   ras derived from "Rat Sarcoma"
See Related English:   Genes, ras
 
History Note English:   95 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   32053 
Unique Identifier:   D018631 

Occurrence in VHL:
 

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